痴呆性疾患患者におけるHDS-RとMMSE得点の比較検討

Comparative Examination of the HDS-R and MMSE Scores in Patients with Dementing Disorders

抄録

　アルツハイマー型痴呆（ATD）群448名，血管性痴呆（VaD）群94名，レビー小体型痴呆（DLB）群21名，前頭側頭型痴呆（FTD）群27名において，改訂長谷川式簡易知能評価スケール（HDS-R）とMini-Mental State Examination（MMSE）得点の差異を検討した。その結果，ATD群はMMSEに比べてHDS-Rが有意に低得点であり，他群ではこのような差はみられなかった。また，下位項目ではVaD群とDLB群は描画課題の正答率が低いことなど，痴呆性疾患によって認知機能障害に差異があることが示唆された。

Summary

　The difference between the scores of the revised version of Hasegawa's dementia scale (HDS-R) and the Mini-Mental State Examination (MMSE) was examined in an Alzheimer-type dementia (ATD) group (448 patients), a vascular dementia (VaD) group (94 patients), a dementia with Lewy bodies (DLB) group (21 patients) and a frontotemporal dementia (FTD) group (27 patients). Our results showed that the HDS-R score was significantly lower than the MMSE score in the ATD group, but there were no significant differences in the other groups. In the sub tasks the ATD group showed difficulty in the “recall” task. The “copy design” task revealed more inadequacy in the VaD and DLB groups than in the other groups. The FTD group was characterized by a low correlation between the difficulty of the task and the scores. In conclusion, it may be said that the characteristics of cognitive impairment in various dementing disorders may be reflected in these scores.