Kokyu to Junkan Volume 45, Issue 8 (August 1997)

Heart Rate Variation during Sleep in Obstructive Sleep Apnea Syndrome:A case report Toshihiko Kubo 1 , Ryuichi Nakaike 1 , Tomoki Yoshida 1 , Shunichi Kaseda 1 , Naoko Ishii 2 , Tsuyoshi Ejima 2 , Kenichi Arita 2 1Department of Cardiology, Hiroshima Red-Cross Hospital and Atomic Bomb Survivors Hospital 2Department of Respiratory Disease, Hiroshima RedCross Hospital and Atomic Bomb Survivors Hospital Keyword: 睡眠時無呼吸症候群 , sleep study , 心拍数変動 , sleep apnea syndrome , heart rate variation pp.817-820
Published Date 1997/8/15
DOI https://doi.org/10.11477/mf.1404900053
  • Abstract
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We analyzed the heart rate variation (HRV) during sleep in a case of sleep apnea syndrome. A 34-year-old man was admitted because of dyspnea and somnolence. He was markedly obese. During sleep he showed sinus tachycardia and cyclic variation of heart rate associat-ed with apnea. With weight reduction and uvlopalato-pharyngoplasty, his symptoms and arterial blood gas were improved,: apnea index 41.1 → 13.5, PaO2 38.0 → 76.3 Torr, and PaCO2 69.5 → 42.0 Torr. Sinus ta-chycardia observed during sleep diminished dramati-cally. HRV was evaluated using spectral variables of low frequency (LF) and high frequency (HR) components, and the LF/HF ratio was determined from Holter recordings. After treatment, the HF component was increased from 30 to 415 msec2 and the LF/HF ratio was decreased from 2.22 to 1.61. Thus, accelerated sympa-thetic activation, triggered by hypoxia and hypercapnia, may result in an unusual sinus tachycardia during sleep.

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45巻8号 (1997年8月)
電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院