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Left ventricular function in patient with diabetes mellitus:Evaluated by mechanocardiogram and echocardiogram Yutaka Okamoto 1 , Eise Yokoyarna 2 , Tadashi Nakanishi 1 , Takeo Yoshinouti 1 , Takehide Mitogawa 1 1Department of Internal Medicine, Matsuyama Shimin Hospital 2Department of Public Health, School of Medicine, Nihon University pp.1327-1331
Published Date 1989/12/15
DOI https://doi.org/10.11477/mf.1404205597
  • Abstract
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We measured cardiac functions by means of me-chanocardiogram and echo-cardiogram in 93 patients with diabetes mellitus, excluding those who had ap-parent cardiac diseases, such as angina pectoris and cardiac failure.

We used pre-ejection-period/ejection time (PEP/ ET) as the index of the left ventricular systolic funct-ion and isovolumic relaxation time (IRT) as that of the left ventricular diastolic function.

We compared the diabetic cases without complica-tions to those with complications such as retinopathy, nephropathy, neuropathy and autonomic disorder. Conclusions obtained were as follows ;

An abnormal IRT was noted in the early stage of diabetic complications. The IRT was not normal among the subjects even when those with cardiac hypertrophy or ST-depression on the ECG were excluded.

On the contrary, the PEP/ET did not show any abnormality in the early stage of diabetic complica-tions until they advanced into, eg. renal failure or severe neuropathy.

Our findings suggest that the disorder of the left ventricular diastolic function precedes that of the left ventricular systolic function, indicating the associa-tion of microangiopathy and autonomic disorder.


Copyright © 1989, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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