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Acute aortic regurgitation due to Takayasu arteritis Naoki Isaka 1 , Yasuo Futagami 1 , Masahiro Sugawa 1 , Takeshi Nakano 1 , Hideo Takezawa 1 , Minoru Kusagawa 2 1The 1st Department of Internal Medicine, Mie University 2The Department of Thracic Surgical, Mie University pp.899-904
Published Date 1986/8/15
DOI https://doi.org/10.11477/mf.1404204918
  • Abstract
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We experienced a 16 year old female with acute aortic regurgitation due to annulo-aortic ectasia caused by Takayasu's arteritis. The patient was well until 3 weeks p.t.d. when she developed fever (37.5c), produ-ctive cough and slight back pain, she was hospitalized because of orthopnea. Examination on admission, blood pressure was 104/40mmHg, heart rate 96/min. and grade 3/6 systolic murmur and diastolic murmur was heared. Serologic test was negative for syphilis, tuber-culosis, antinuclear body or viral titer. Chest X-ray revealed pulmonary edema and EKG showed nonspecific ST change. Echocardiogram showed marked dilatation of aortic root with sinus of Valsalva and also early closure of mitral leaflet. Aortogram confirmed the presence of aortic regurgitaion due to annulo-aortic ectasia, but not associated with involvement of other arterial branches. Histologic study disclosed fibrous thickening of intima and adventitia, and inflammatory cells, granuloma with giant cells and destruction of smooth muscle were pre-sent in media. Clinical and histlogical features suggest Takayasu's arteritis. It is rare that acute aortic regurgita-tion due to annuloaortic ectasia without other occulu-sive change in Takayasu's arteritis.


Copyright © 1986, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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