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Clinical significance of exercise-induced ST-segment depression in inferior leads in patients with anterior myocardial infarction Kunitomo Satoh 1 , Nobuhisa Ohgitani 1 , Shigemi Kanoh 1 , Sugao Hukui 2 , Takazo Minamino 2 , Hoga Kim 3 1Division of Cardiology, North Osaka Hospital 2Division of Cardiology, Sakurabashi Watanabe Hospital 3The First Department of Internal Medicine, Osaka University Medical School pp.1017-1023
Published Date 1985/8/15
DOI https://doi.org/10.11477/mf.1404204727
  • Abstract
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In order to evaluate clinical significance of exer-cise-induced ST depression (ST ) in inferior leads (III, aVF) in patients with first anterior transmural myocardial infarction (ML, 108 patients with an-terior MI were performed symptom-limited multi-stage exercise test in supine position using a bicycle ergometer about two months after the onset of MI. 12-lead ECG was obtained before and during the exercise test. CAG and LVG were performed by Judkins' technique.

Results : 1) 18 of 108 patients (44.4%) had ST↓, in leads III and aVF during exercise test, 56 (51.9%) no ST change (ST→) and 4 (3.7%) ST elevation (ST↑). 2) While no significant rela-tion of exercise-induced ST change to age, sex, exercise tolerance and rate pressure product at the endpoint of exercise test, 14 of 17 patients who hadchest pain during exercise test had exercise-induced ST↓.3) 19 of 18 patients (39.6%) with exercise-induced ST↓ had multivessel disease. On the other hand, 29 patients (60.4%) had single vessel disease (SVD) or no significant coronary artery lesion (OVD). 4) While only one of 39 patients with SVD or OVD who had ST ; in leads V1~6 had ST↓ in leads III and aVF, 20 of 21 patients (95.2%) with ST t in leads I or aVL had ST↓in leads III, aVF. 5) S of 20 patients who had ST→ in anterior leads had ST↓) in inferior leads. These patients had severe coronary artery narrow-ing in proximal portion of LAD.

These findings indicate that mechanism of ST↓in III, aVF were (1) coronary artery lesion of vessel related to inferior area, (2) reciprocal chan-ges of ST↑ in leads I, aVL and (3) ischemia around anterior infarct.


Copyright © 1985, Igaku-Shoin Ltd. All rights reserved.

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