Stomach and Intestine(Tokyo) Volume 54, Issue 6 (May 2019)

Definition and Endoscopic Diagnostic Criteria for PG Type Early Cololectal Tumors:Including Differences from NPG Type Tumors Hiro-o Yamano 1 , Toshiyuki Kubo 1 , Kei Mitsuhashi 1 , Gota Sudo 1 , Yasuhiro Shibata 1 , Hiroshi Nakase 1 1Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Sapporo, Japan Keyword: PG type , NPG type , 大腸腫瘍 , 早期大腸癌 , 大腸腺腫 , 拡大内視鏡 pp.819-831
Published Date 2019/5/25
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 We examined the possibility to differentiate polypoid growth type(PG)/non-polypoid growth type(NPG)of colorectal tumors by endoscopic diagnosis. The samples were 172 colorectal adenomas and early-stage cancer lesions(including serrated lesion), which were observed by both magnifying endoscopy in vivo and stereomicroscopy in vitro at Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine. Protruded, flat-elevated, and depressed lesions were extracted from these lesions. The characteristics of magnifying endoscopic findings were compared with histopathology, in particular we focused on whether the developmental progress of the marginal part of the lesion was polypoid growth or non-polypoid growth. As a result, PG/NPG could be differentiated by confirming the intercalation of type I pit at the boundary between the neoplastic lesion and surrounding normal mucosa. However, some cases contain uncertain factors that cannot be determined. Moreover, PG/NPG has been considered to have a lesser significance in clinical research because of diversity in the developmental progress of colorectal tumors, which is proven by translational research.

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54巻6号 (2019年5月)
電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院