A Useful Marker Instead of the Vessel Plus Surface Classification System:White Opaque Substance Hiroyoshi Nakanishi 1 , Hisashi Doyama 1 1Department of Gastroenterology, Ishikawa Prefectural Central Hospital, Kanazawa, Japan Keyword: NBI , 拡大内視鏡 , 胃癌 , 白色不透明物質 , WOS pp.202-205
Published Date 2019/2/25
DOI https://doi.org/10.11477/mf.1403201580
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 WOS(white opaque substance)is a novel endoscopic finding that is frequently found in the intestinal metaplasia of chronic gastritis mucosa or gastric neoplasms. WOS is an accumulation of lipid droplets within the epithelium and subepithelium ; it appears white because the light projected by the endoscope is intensely scattered or reflected on the surface. The visibility of the blood vessel is low because the projected light does not reach the microvessel under the epithelium. The morphology of the WOS is a useful marker for differentiating whether the lesion is cancer or non-cancer.

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