Gastric Hyperplastic Polyps Toshifumi Ohkusa 1 , Hiroshi Horiuchi 2 , Hiroshi Arakawa 1 , Mitsuru Kaise 3 , Hisao Tajiri 2 1Department of Gastroenterology and Hepatology, The Jikei University Kashiwa Hospital, Kashiwa, Japan 2Department of Gastroenterology and Hepatology, The Jikei University school of Medicine, Tokyo 3Department of Gastroenterology, Toranomon Hospital, Tokyo Keyword: 胃過形成性ポリープ , 癌化 , H. pylori感染 , 除菌療法 , ガストリン pp.1216-1226
Published Date 2012/7/25
DOI https://doi.org/10.11477/mf.1403113545
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 Gastric hyperplastic polyps represent the commonest polyp in the stomach, however they are rare, found in only about 2% of cases. It is a disease not encountered much in clinical practice. The endoscopic finding is a red polyp like a decaying strawberry. A flare-like localized upheaval lesion. It may be accompanied by a sore and white moss on the surface. The background mucosa usually appears as atrophic gastritis. The pathological finding presents an inflammatory polyp with hyperplasia of the foveolar epithelium and strong inflammation and edema of the mucosa. In addition, it is rare for this lesion to naturally decrease in size or disappear. An average of 2.2% of cases undergo malignant transformation. This is reported as(0~9.7%). H. pylori infection associated with the hyperplastic polyps occurs at a high rate, reported to be 76~100%. H. pylori eradication therapy is a treatment for these hyperplastic polyps. In non-responsive cases which do not disappear after success in H. pylori eradication, hypergastrinemia usually continues. Therefore, gastrin is suggested at the cause of the growth of the hyperplastic polyp.

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