A Follow-up of Group 2 Lesions According to the Old and New Classifications by Endoscopic Re-examination Junko Fujisaki 1 , Natsuko Yoshizawa 1 , Noriko Yamamoto 2 , Yo Kato 2 , Sho Suzuki 1 , Manabu Kubota 1 , Chika Taniguchi 1 , Masami Omae 1 , Kazuhisa Okada 1 , Yasumasa Matsuo 1 , Yusuke Horiuchi 1 , Takanori Suganuma 1 , Yorimasa Yamamoto 1 , Toshiaki Hirasawa 1 , Akiyoshi Ishiyama 1 , Tomohiro Tsuchida 1 , Etsuo Hoshino 1 , Masahiro Igarashi 1 1Endoscopy Division, Cancer Institute Hospital, Tokyo 2Pathology Division, Cancer Institute Hospital, Tokyo Keyword: Group分類 , Group 2 , 胃癌 pp.174-185
Published Date 2012/2/25
DOI https://doi.org/10.11477/mf.1403113093
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 Pathogenic diagnosis has been described without using the group classification in our hospital, and the term atypical epithelium(AE)has been used when it is difficult to differentiate between regenerative atypia and cancer. A total of 82 cases diagnosed with AE between January 2009 and December 2010 were examined. There were 70 cases that were followed-up with re-biopsy, and 19 of them were diagnosed with gastric cancer. Nine cases did not undergo re-biopsy and were treated by ESD because gastric cancer was diagnosed solely by magnifying endoscopy combined with NBI, in three of which gastric cancer was not observed. Gastric cancer was finally diagnosed in 33 cases(40%). A follow-up examination one month later revealed gastric cancer in 19 of 40 cases(48%). Gastric cancer was diagnosed in 11 of 32 cases(34%)three months later and 3 of 16 cases(19%)six months later. About half of lesions corresponding to Group 2 according to the new classification were likely to be cancer and a follow-up and re-biopsy were necessary. Magnifying endoscopy combined with NBI was carried out in 38 cases, of which 23 cases(61%)were diagnosed accurately, and some cases were difficult to diagnose.

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