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Fundic Gland Polyposis not Associated with Adenomatosis of the Colon M. Iida 1 , T. Yao 1,2 , H. Watanabe 3,4 , S. Fuyuno 5 , T. Omae 1 1The Second Department of Internal Medicine, Faculty of Medicine, Kyushu University 3The Second Department of Pathology, Faculty of Medicine, Kyushu University 5Fukuoka City Medical Association Hospital pp.1111-1118
Published Date 1980/10/25
DOI https://doi.org/10.11477/mf.1403112829
  • Abstract
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 We have reported previously that fundic gland polyposis consisting of simple hyperplasia of fundic glands seems to be the gastric lesion specific to familial adenomatosis coli syndrome. In this study, nine patients (group A) not associated with adenomatosis of the colon but with fundic gland polyposis were reported, and were compared with twelve patients (group B) associated with both lesions.

 1) Age and sex: The average age was 48.0 years (32 to 65) in group A, and 25.3 years (11 to 41) in group B. Group A included 3 males and 6 females, while group B, 7 males and 5 females. The age of group A was significantly higher than that of group B (p=0.01).

 2) Characteristics of polyps: Fundic gland polyposis in group A was most commonly distributed in the middle and lower part of the gastric body. These polyps were multiple (2 to 50 in number), measuring up to 8 mm in the greatest dimension, and sessile or subpedunculated with a smooth surface. Only one patient had three pedunculated and relatively large polyps. On the other hand, the number of polyps in group B was larger (over 100) than that of group A. In addition, the polyps in group B were sited either diffusely from the fornix to the lower part of the body or lacally in the fornix. Therefore, we found that it is possible to differentiate group A from group B only through x-ray examinations of the stomach.

 3) Follow up of polyps: Eight patients in group A were followed up by x-ray examination of the stomach and gastro-fiberscopy. In five patients (32 to 55 years, female), multiple polyps disappeared or decreased in number and size in the course of seven months to about three years. The polyps of the remaining three patients (52 to 65 years, male) showed no remarkable change in number and size in the course of a year to about six years.


Copyright © 1980, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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