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多発性Ⅱc型早期胃癌に類似した肉眼像を呈し,組織学的にreactive lymphoreticular hyperplasia(以下RLH)と悪性リンパ腫が共存した1例を報告する.
症 例
患 者:55歳,女.
主 訴:胃の精査.
現病歴:特に自覚症状はなかったが,胃集団検診にて異常を指摘されたため1970年2月来院.
A 55-year-old woman was told to have abnormal finding at the mass screening for gastric cancer in spite of having no subjective symptoms. She was hospitalized for examination in February 1970. Roentgenographic and endoscopic study of the stomach revealed multiple irregular shallow ulcers and a granular mucosal pattern, extending from the body to the antrum. The border of the lesion was indistinct. Though histologic study of the biopsy specimens was negative for carcinoma, she was diagnosed as having multiple Ⅱc-type early cancers of the stomach.
She underwent subtotal gastrectomy in March 1970. Histologic study of the resected stomach revealed malignant lymphoma (2×1. 2 cm, diffuse lymphoma, poorly differentiated histiocytic type) involving the mucosa and submucosa on the anterior wall of the body. In addition, histology of the mucosa surrounding the tumor was that of RLH.
Therefore, this case may suggest the possibility of malignant change of RLH.
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