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On the Special Features in This Issue on Crohn's Disease H. Okabe 1 1Dept. of Internal Medicine, School of Medicine, Kitasato University pp.1009-1013
Published Date 1975/8/25
DOI https://doi.org/10.11477/mf.1403112339
  • Abstract
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 Crohn's disease was made known in 1932 as an affection involving the terminal end of the ileum, but it has been subsequently made clear that not only the terminal ileum but the other segments of the ileum, jejunum and even colon could be affected as well. Indeed all the parts of the digestive tract are now considered to be affected by it. However, its etiology remains unclarified yet, and there are no distinct histologic pictures specific to this disease. Further, its clinical manifestations are so variegated according to the segments involoed that even a suspicion is entertained whether or not this disease could be a single clinical entity.

 In western countries it has aroused special interest among those connected with the diseases of the gastrointestinal tract including internists, surgeons, radiologists, pathologists and more recently immunologists. An immense number of reports and studies are therefore published from year to year. Nevertheless, the results of immunologic studies based on the latest investigational methods remain conflictory. The pathogenesis of this affection is still hidden, as it were, in a veil of mystery.

 In Japan reports of typical cases initially described by Crohn have been so far and few between that not much interest was displayed in this subject. However, with its enlarged definition and with increasing concern about the diffrentiation between it and ulcerative colitis now becoming more frequent here, we are compelled to pay more attention to this disease.

 Crohn's disease has been taken up in this issue as special features in the expectation that active progress be made in this country for independent study of this disease.

 Finally, the names and their comments are described relevant to the papers from Council for International Organizations of Medical Sciences recommended for international use as a complement to the WHO International Classification of Diseases (1974).


Copyright © 1975, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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