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Splenomegaly-From the pathological and anatomical point of view. Morio Koike 1 1Department of Pathology, Toranomon Hospitol pp.755-763
Published Date 1974/6/25
DOI https://doi.org/10.11477/mf.1403111905
  • Abstract
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 Enlargement of the spleen is considerably common in various diseases, such as hematological disorders includingleukemia and malignant lymphoma, Banti's syndrome and liver cirrhosis, various kinds of infection, storage diseases and rarely splenic neoplasms, although histopathological appearances differ from case to case. Although clinical signs and symptoms depend upon the fundamental diseases causing splenomegaly, some show signs of hypersplenism, obstruction of the G-Ⅰ tract due to compression by the enlarged spleen, and infiltration of the splenic tumor into the wall of the G-I tract resulting in massive hemorrhage.

 In this report 5 cases with splenomegaly, including two of primary malignant neoplasma of the spleen and one of splenic cyst, are mentioned.

 Malignant neoplasms of the spleen are very rare. There have been three primary malignant neoplasms of the spleen in 2600 autopsy cases at Toranomon Hospital for the past fifteen years. According to Ahmann, who reported 49 cases of primary malignant lymphoma of the spleen, its incidence is less than 1% of total malignant lymphomas. Of the 49 patients, preoperative diagnoses were malignant lymphoma in 23, and indeterminate splenomegaly, hypersplenism, and Banti's syndrome in the others. Since Skarin emphasised the good prognosis in 11 cases of primary lymphosarcoma of the spleen, indication for splenectomy should be considered whenever occasion arises.


Copyright © 1974, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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