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Endoscopic Sclerothrombotherapy for Esophageal Varices: Technique and Long Term Follow-up of ETP Method Hiroyasu Makuuchi 1 , Yutaka Tanaka 1 , Takashi Sugihara 1 , Toshio Mitomi 1 , Hirofumi Shiina 2 1Department of Surgery, Sclool of Medicine, Tokai University 2Department of Internal Medicine, Sclool of Medicine, Tokai University pp.497-505
Published Date 1985/5/25
DOI https://doi.org/10.11477/mf.1403109822
  • Abstract
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 Recently, endoscopic sclerothrombotherapy for esophago-cardiac varices is becoming increasingly popular in Japan. This therapeutic method is effective not only for emergency hemostasis, but also for permanent elimination of the varices. In 1983, we commenced new sclerothrombotherapy using anhydrous alcohol, human thrombin and 1% Aethoxysklerol. This is called the ETP method. This procedure has been carried out a total of 723 times in 183 cases. The rate of hemostasis for emergency cases was 93.8% and 158 cases of them (86.3%) resulted in almost complete disappearance of varices. Only 8 cases, 4.4%, died of hepatic failure after bleeding.

 Concerning complications, mild pain or dysphagia was seen in about 50% of cases, but no other severe complications were seen. As for the long term follow-up, about 4.7% of them recurred low grade varices after six months and only 8.9% after 12 months. Rebleeding occurred in only tow cases.

 The authors feel that endoscopic sclerothrombotherapy will be the first choice for the treatment of esophago-cardiac varices in the near future, but some problems still remain to be solved.


Copyright © 1985, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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