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Adenomatosis Coli Associated with Large Adenomas of the Major and Minor Papillae K. Sugihara 1 , T. Muto 1 , Y. Kubota 1 , Y. Morioka 1 1The First Department of Surgery, Faculty of Medicine, Tokyo University pp.673-677
Published Date 1984/6/25
DOI https://doi.org/10.11477/mf.1403107053
  • Abstract
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 A 28 year-old man with complaint of rectal bleeding was found to have familial adenomatosis coli and received total colectomy with ileorectal anastomosis in September 1974. Histologic examination disclosed numerous tiny adenomas throughout the Iarge bowel without advanced carcinoma. He was followed up with colonoscopy and polypectomy of the preserved rectum several times a year. Three times of barium meal examination of upper gastrointestinal tract showed no polyps of the stomach and duodenum. In April 1983 gastroduodenoscopy, which was performed for the first time, revealed the enlarged major and minor papillae and several tiny polyps of the duodenum, without any polyps in the stomach. He was asymptomatic and clinical laboratory examinations showed no abnormal values. Local excision of tumors was performed through duodenotomy. Histologically, both tumors of the major and minor papillae were adenomas without any malignant change.

 Until recently, surveillance of patients with adenomatosis coli who had received prophylactic colectomy has been restricted to examination of the rectum. However, recent studies disclosed the frequent presence of polyps in the stomach and duodenum in patients with adenomatosis coli, and 35 cases of periampullary carcinoma associated with adenomatosis coli were reported in the world literature. It is necessary to perform periodic upper gastrointestinal endoscopy in following up of polyposis patients in order to detect malignancy of the stomach and duodenum in its early stage.


Copyright © 1984, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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