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Duodenal Carcinoid (Somatostatinoma) Diagnosed by Endoscopic Biopsy and Hypersomatostatinemia, Report of a Case Toru Nakanishi 1 , Tadashi Takeuchi 2 , Takahiro Tsujimura 3 , Yoshitada Tamatani 4 1Department of Internal Medicine, Sumitomo Hospital 2Department of Surgery, Sumitomo Hospital 3Department of Pathology, Sumitomo Hospital 4Osaka Kankho Health Insurance Center pp.950-954
Published Date 1989/8/25
DOI https://doi.org/10.11477/mf.1403106546
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 A rare case of duodenal somatostatinoma, which was diagnosed by endoscopic biopsy and hypersomatostatinemia was reported.

 A 59-year-old man was under follow-up tests after a duodenal polyp. This polyp was located at the anterior wall of the duodenal cap, and was associated with a small erosion on the top (Figs. 2 and 3). Diagnosis as carcinoid tumor was made by endoscopic biopsy. Hypersomatostatinemia (160 pg/ml) was confirmed, and the diagnosis of somatostatinoma was made.

 The tumor, 8×7×4 mm in size (Fig. 4), was found after surgical operation. Microscopic examination revealed a carcinoid which showed a glandular pattern. Infiltration was limited to the submucosal layer (Figs. 5 and 6). Somatostatin was identified in the tumor cells by immunocytochemistry (Fig. 7). After the operation, serum Somatostatin level returned to normal limits (8.2 pg/ml).

 This is the fourth case of duodenal somatostatinoma (Table 2) and the first case of this tumor diagnosed before surgical operation, even reported in Japan.


Copyright © 1989, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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