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Generalized Juvenile Gastrointestinal Polyposis Complicated with Colon Cancer and Breast Cancer, Report of a Case Ichiro Hirata 1 , Gakuji Adachi 1 , Saburo Ohshiba 1 , Kunio Okajima 2 , Akio Kurokawa 3 1The Second Department of Internal Medicine, Osaka Medical College 2Department of General and Gastroenterological Surgery, Osaka Medical College 3Pathology Unit of Central Laboratory Department, Osaka Medical College Keyword: 若年性胃腸管ポリポーシス , 大腸癌 , 乳癌 , 色素沈着 , 口腔内乳頭腫様病変 pp.1363-1372
Published Date 1993/11/25
DOI https://doi.org/10.11477/mf.1403106321
  • Abstract
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 A 51-year-old female who had anemia, multiple verruciform pigmentations in her trunk and papillomatous lesions in her lower lip mucosa was referred to our department in order to examine the cause of anemia. Roentgenographic and endoscopic examinations revealed numerous small polyps in the body of the stomach and seven polyps in the large intestine. The histological examinations of the polyps showed characteristic features of juvenile polyp. In one of colonic polyps which measured about 3 cm in diameter, well differentiated adenocarcinoma (submucosal invasion) and juvenile polyp hamartoma coexisted. Moreover, she had right breast cancer (papillotubular adenocarcinoma). This patient is considered to be the first case in juvenile polyposis, with the complications of breast cancer, body pigmentation and papillomatous lesion in the oral cavity. It should be stressed that patients with juvenile polyposis should undergo cancer surveillance not only of the gastrointestinal tract but also of other organs.


Copyright © 1993, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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