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Management of the Colonic Lesions of Familial Adenomatous Polyposis from the Viewpoints of Long-term Follow-up Masaaki Yamashiro 1 , Kyosuke Ushio 1 , Tsutomu Ishikawa 1 , Yoshihiro Moriya 3 , Tadakazu Shimoda 5 1Department of Diagnostic Radiology, National Cancer Center Hospital 3Department of surgery, National Cancer Center Hospital 5Department of pathology, Division of Clinical Laboratory. National Cancer Center Hospital Keyword: 家族性大腸腺腫症 , 結腸全摘回腸直腸吻合 , 経過観察 , 大腸進行癌 pp.551-561
Published Date 1997/3/25
DOI https://doi.org/10.11477/mf.1403105099
  • Abstract
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 During the period of 30 years between November 1996 and October 1996, 78 cases of familial adenomatous polyposis were diagnosed and followed in the National Cancer Center Hospital. Fifty six cases underwent colectomy, 22 of them were treated by the total colectomy with ileo-rectal anastomosis (IRA). Eight out of 17 cases treated by IRA and followed more than three years developed cancer in the residual rectum. The average follow-up period between the initial and second operations was 13.7 years. Three out of eight cases developed advanced cancers, but all of them missed regular follow-up visits and did not receive adequate evaluation over a long period of time. On the other hand, those who received regular follow-up examinations did not develop advanced cancer but early cancer. These results suggest that FAP patients treated by IRA may develop advanced cancer within 10 years if not followed properly, therefore those who underwent the operation for FAP which preserved the rectum should be evaluated at least once a year.


Copyright © 1997, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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