雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Clinical Characteristics of Multiple Colorectal Cancers Shin Fujita 1 , Yoshihiro Moriya 1 , Takayuki Akasu 1 1Department of Surgery, National Cancer Center Hospita Keyword: 大腸多発癌 , 遺伝性非ポリポーシス大腸癌 , 多発癌発生間隔 pp.989-994
Published Date 2000/7/25
DOI https://doi.org/10.11477/mf.1403104754
  • Abstract
  • Look Inside

 In order to clarify clinical characteristics of multiple colorectal cancers, we examined the clinicopathological backgrounds of patients with multiple colorectal cancers and compared them with those of patients with single cancer. 4,028 colorectal cancer patients with more than pT2 tumors were treated consecutively at the National Cancer Center Hospital from 1963 to 1998. Among them, 153 patients (4%) were found to have multiple colorectal cancers. Hereditary non-polyposis colorectal cancers (HNPCCs) were not included. There was a higher ratio of multiple cancers than single cancers in both male and female subjects. This was significant among synchronous multiple cancers (p=0.0002). Because the patients with multiple colorectal cancers had some of the characteristics of HNPCC such as a high incidence of right colon cancer, and a higher incidence among the young. Some HNPCC patients who do not fulfill HNPCC criteria might be included among the patients with multiple cancers. Prognosis of patients with synchronous multiple cancers was worse than that of patients with single cancer, but it was not significant. Incidence of multiple colorectal cancers was biphasic with a peak during the first 2~3 years and another after 8~9 years. There was some unnoticed synchronous cancers or adenomas in the first peak. Thus, careful examination to detect another lesion at the original cancer diagnosis was important for preventing metachronous cancers.


Copyright © 2000, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

関連文献

もっと見る

文献を共有