What is the Most Effective Method of Cutting in a Routine Examination of Endoscopically Resected Gastric Specimens with Early Carcinoma ? Kazuo Nakano 1 1Department of Pathology, Cancer Institute Keyword: 早期胃癌 , 内視鏡的粘膜切除 , EMR pp.1067-1072
Published Date 1996/8/25
DOI https://doi.org/10.11477/mf.1403104220
  • Abstract
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 As a routine pathological examination of endoscopically resected (EMR) gastric specimens with carcinoma, we have adopted a method of cutting a specimen at 2 mm interval and perpendicularly to its long axis (the "standard" method) at least five years. If the specimen is cut at less than 2 mm interval, it becomes practically difficult to treat with cut-specimens during the process. Although the“standard”method has given us very accurate information on carcinomatous involvement of cut margins and the submucosal layer, it is rather complicated. Therefore, to find a simpler or more effective way, eight methods of cutting in addition to the standard one (as shown in Fig. 1) were evaluated using 80 EMR specimens with an early gastric carcinoma As a result, as long as specimen was cut perpendicularly to its long axis, diagnostic accurary at 3 mm interval was almost the same as that at 2 mm interval. Methods to cutting at more than 3 mm interval, cutting parallel to the long axis or to make cross sections were clearly less accurate. Since the above results were obtained from the specimens with carcinomas of differentiated type, it would be necessary to analyze specimens with carcinoma of undifferentiated type in the future.

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