Aphthoid Colitis as a Preceding Lesion of Ulcerative Colitis, Report of a Case Masaharu Takeda 1 1Division of Gastroenterology, Department of Medicine, Kawasaki Medical School Keyword: 潰瘍性大腸炎 , アフタ様病変 , 発作性夜間血色素尿症 pp.1279-1285
Published Date 1998/8/25
DOI https://doi.org/10.11477/mf.1403103804
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 A 65-year-old man with a previous diagnosis of paroxysmal nocturnal hemoglobinuria was referred to our division, because of positive fecal occult blood. Colonoscopy showed multiple aphthoid lesions, which were predominantly located from the ascending colon through descending colon. These lesions subsequently extended to the rectum and, thereafter, developed in rough-surfaced mucosa and multiple erosions of a segment in the descending and sigmoid colon. Seven months later, colonoscopy and barium enema examination revealed that the aphthoid colitis had progressed to typical ulcerative colitis of entire type. This case seems to be suggestive of the initial lesions and their pregression to ulcerative colitis, which have been still poorly investigated to date.

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