Histological Diversity of Serrated Adenoma Tadakazu Shimoda 1 , Makoto Saka 1 1Department of Pathology, Clinical Laboratory Division, National Cancer Center Hospital Keyword: 過形成性ポリープ , 鋸歯状腺腫 pp.831-834
Published Date 1998/5/25
DOI https://doi.org/10.11477/mf.1403103719
  • Abstract
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 Histologically, there is a wide spectrum (variety) of color polyps associated morphologically with the serrated structure of proliferative glands. Hyperplastic polyps are distributed commonly in sizes less that 10 mm, but hyperplastic polyps more than 10 mm in size consist of immature glands, which show an extended proliferative zone labeled by Ki-67 antibody. These polyps present not only a papillary pattern but also budding fomation similar to that seen in serrated adenoma. This polyp is sometimes confused with serrated adenoma. The serrated adenoma is a true neoplastic lesion while, histologically proliferative glands appear as adenomas with a dense and spindle-shaped nucleus which is stained by Ki-67.

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