Japanese

Significance of the Histological Special Type of the Gastric Carcinoma in the 14 th Edition of the JGCA Classification Tamon Miyanaga 1 , Yasuharu Kaizaki 2 , Osamu Hosokawa 3 , Yoshihide Asaumi 1 , Homare Ito 1 , Kouichiro Sawada 1 , Yasuo Hashizume 1 1Department of Surgery, Fukui Prefectural Hospital, Fukui, Japan 2Department of Pathology, Fukui Prefectural Hospital, Fukui, Japan 3Department of Surgery, Yokohama Sakae Kyosai Hospital, Yokohama, Japan Keyword: 胃癌 , 特殊型 , リンパ球浸潤癌 , 腺扁平上皮癌 , 予後 pp.1882-1893
Published Date 2010/11/25
DOI https://doi.org/10.11477/mf.1403102056
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 Four hundred and sixty-eight patients who had gastric cancer with invasion deeper than the submucosal layer and whose outcome was determined were examined, focusing on special type gastric carcinoma based on the 14th edition of the Japanese Classification of Gastric Carcinoma. Of the 468 patients, 43(9.1%)were classified as special type, consisting of 8 with endocrine cell carcinoma, 14 with hepatoid adenocarcinoma, and 21 with carcinoma with lymphoid stroma. According to the histological typing of the 13th edition, these patients included 32 patients with por 1, 4 patients with pap, 4 patients with tub 2, 1 patient with tub 1, 1 patient with por 2, and 1 patient with nec. The outcome of all the patients was determined, and 5-year survival rates were 25.0% for endocrine cell carcinoma and 35.7% for hepatoid adenocarcinoma. These rates were significantly lower compared with the survival rate of 66.0% in all patients who had gastric cancer with invasion deeper than the submucosal layer. The 5-year survival rate was 95.2% in patients who had carcinoma with lymphoid stroma, which was significantly high. Our previous 5 and 4 patients not included in this study had been classified as squamous cell carcinoma and adenosquamous carcinoma, respectively ; but, when they were reexamined according to the 14th edition, only 1 patient was classified as squamous cell carcinoma and 4 patients as adenosquamous carcinoma. Special type gastric carcinoma is difficult to diagnose because of its low frequency ; but, the present 14th edition of Japanese Classification of Gastric Carcinoma will increase the cases of special type gastric carcinoma, and its importance is expected to increase.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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