Non-epithelial Tumors in the Rectum and the Anus Tetsuo Yamana 1 , Rikisaburo Sahara 1 , Maki Tezuka 2 , Koichi Kobayashi 2 , Taishi Tsuji 3 1Coloproctology Center, Social Health Insurance Hospital, Tokyo 2Department of Obstetric and Gynecology, Social Health Insurance Hospital, Tokyo 3Toshimaen Coloproctology Clinic, Tokyo Keyword: 直腸非上皮性腫瘍 , GIST , 平滑筋性腫瘍 , 悪性黒色腫 , 転移性腫瘍 pp.1371-1379
Published Date 2010/7/25
DOI https://doi.org/10.11477/mf.1403101991
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 Non-epithelial tumors in the rectum and the anus are very uncommon disorders, which include GIST, leiomyoma, leiomyosarcoma, and lipoma and so on. Clinically, these tumors are diagnosed as submucosal tumor by endoscopy or barium enema. GIST and leiomyoma are differentiated by immunohistochemical stain. GIST and leiomyoma should be treated as a malignant tumor, and imatinib is effective for recurrent GIST. Lipoma of the rectum is also rare. Usually no treatment is justified, but liposarcoma may have developped. Occasionally a malignant melanoma develops in the anorectal region, which has extremely poor prognosis. Metastatic tumor in the rectum is rare. Spread from adjacent primary neoplasms is perhaps more common than blood-borne spread.

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