5)acanthosis nigricans（黒色表皮腫）

Acanthosis Nigricans

　黒色表皮腫(acanthosis nigricans)は皮膚の色素沈着，角質増生，乳頭状増殖を3微とし種々の病変に合併する皮膚疾患である．合併疾患としては内臓悪性腫瘍，特に胃癌に多く報告がみられるが，今回われわれは大腸癌に合併した比較的まれな症例を経験したので提示する．

　Acanthosis nigricans is a skin disease showing triad signs of skin pigmentation, hyperkeratosis and papillary skin hyperplasia. It is well known that this skin disease is accompanied by various human diseases. The most commonly reported visceral organ malignancy coexisting with acanthosis nigricans is gastric cancer. In this article, we reported a rare case of acanthosis nigricans coexisting with colorectal cancer.