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IIc-like Advanced Duodenal Signet-ring Cell Carcinoma, Report of a Case Tsuyoshi Arita 1 , Shunzo Satoh 1 , Hisanori Abe 1 , Kazuaki Hiroishi 1 , Takashi Yao 2 1Arita Gastro-Intestinal Hospital 2Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyusyu University Keyword: 原発性十二指腸癌 , 印環細胞癌 pp.1445-1450
Published Date 2005/9/25
DOI https://doi.org/10.11477/mf.1403100244
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 A 74-year-old woman was hospitalized for further investigations after a positive fecal occult blood test. Hypotonic duodenography revealed an irregular concave lesion, accompanying poor wall extension, located orally on the internal side from the papilla of Vater in the second portion of the duodenum. Upper gastrointestinal endoscopy demonstrated variegated mucosal redness and small protruded nodules in the depressed part of the lesion. Histological examination of biopsy specimens showed signet-ring cell carcinoma. Under a diagnosis of primary duodenal carcinoma, we conducted a pylorus-preserving pancreaticoduodenectomy. In the resected specimen, the tumor was 15×10 mm in size, resembled IIc type with ulceration macroscopically, but, histologically, it was shown to have invaded to the subserosal layer. Six reports showed duodenal signet-ring cell carcinoma cases in Japan, but our case of, IIc-like advanced duodenal signet-ring cell carcinoma, is the first one to be documented in the medical literature in Japan.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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