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The effect of brightness on anterior segment photography in CorneAI: a study on pterygium Airi Mishima 1 , Yuko Nakamura 1 , Atsuhiko Fukuto 1 , Yuta Ueno 2,3 , Tetsuro Oshika 2,3 , Taiichiro Chikama 1 1Department of Ophthalmology and Visual Science, Hiroshima University Graduate School of Biomedical & Health Sciences 2Department of Ophthalmology, University of Tsukuba 3Japan Ocular Imaging Registry pp.1438-1443
Published Date 2025/11/15
DOI https://doi.org/10.11477/mf.037055790790121438
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Abstract Purpose:To investigate how variations in the brightness of anterior segment photographs affect classification accuracy when using a corneal artificial intelligence(AI) classification model(prototype:CorneAI) for diagnostic support, focusing on pterygium cases. This study aimed to enhance the understanding of the characteristics of CorneAI and provide insights for clinical implementation.

Subjects and methods:The study included 12 eyes from 10 patients with pterygium who visited the Ophthalmology Department at Hiroshima University Hospital between July 2023 and September 2023. Diffuser photographs with varying brightness levels(high and low luminance) were captured using a slit-lamp microscope. Classification names and likelihood scores were compared by inputting high-and low-luminance images from the same cases into CorneAI.

Results:All 24 images(12 high-luminance and 12 low-luminance) were classified as tumorous lesions by CorneAI. The likelihood scores for classification were significantly higher for high-luminance images compared to low-luminance images, with a strong positive correlation between the likelihood scores for the high-and low-luminance images(rs=0.892, p=0.0059).

Conclusion:When photographing pterygium cases, brighter illumination clearly shows white pterygium tissue, whereas darker images reveal blood vessel invasion as the tissue appears more transparent. CorneAI tends to classify high-luminance images with higher likelihood scores, offering insights into the features that AI prioritizes when evaluating cases of pterygium.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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