同種大動脈弁組織を用いた大動脈基部再建

Aortic Root Replacement with Homograft

感染性心内膜炎（IE）は心臓血管外科領域における重症感染症である．適切な抗菌薬投与が治療のベースとなるが，感染による組織の破壊を伴う場合や，感染のコントロールが困難で疣贅による塞栓症のリスクが高い場合は，外科的な治療介入が必要である．しかし，術前状態の感染や心不全，塞栓症などで全身状態が悪化している場合も多く，手術リスクは高い．また，周術期の感染コントロールも治療成績に大きく影響する．

Infectious endocarditis is a severe infectious disease in cardiovascular surgery fields. Appropriate antibiotics administration is the principle of treatment, while surgical intervention is required when there is intensive tissue destruction, refractory infection, or high risk of embolism. Usually, surgical risks of infectious endocarditis are rather high as preoperative general condition is often poor. Homografts, which have excellent anti-infective properties, become one of the graft options for infectious endocarditis. Fortunately, we are able to use homografs without so much obstacles thanks to the presence of a tissue bank in our hospital. We will report our strategy and clinical courses of aortic root replacement using homograft for infective endocarditis.