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Management of Delayed Ischemic Neurological Deficit in Subarachnoid Hemorrhage Patients before Aneurysmal Surgery Shinri ODA 1 , Masami SHIMODA 1 , Masayohi SHIBATA 1 , Osamu SATO 1 , Ryuichi TSUGANE 2 1Department of Neurosurgery, Tokai University School of Medicine 2Department of Neurosurgery, Tokai University Oiso Hospital Keyword: Subarachnoid hemorrhage , Rerupture , Delayed ischemic neurological deficit pp.503-507
Published Date 1995/6/10
DOI https://doi.org/10.11477/mf.1436901034

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  • Abstract
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The incidence of rerupture during the period of de-layed ischemic neurological deficit (DIND) was studied in patients with aneurysmal subarachnoid hemorrhage (SAH) before surgical aneurysmal obliteration, and optimal management of DIND for preventing rerupture is discussed.

At Tokai University Hospital, 511 patients with SAH were admitted during the 5-year period from 1988 to 1992. Of these, 247 had not undergone obliteration of the aneurysm neck within 3 days after SAH. In this group, 31% (77 patients) developed DIND. Of these 77 patients, 40 were managed with induced hypertension and/or hypervolemic therapy for DIND (25 with both (group 1), 15 with normotensive hypervolemic therapy (group 2)), and 37 did not receive either kind of the-rapy (group 3). The incidences of rerupture were as follows: all SAH patients: 11.5%; group 1: 48%; group 2: 7%; group 3: 11%. The incidence of rerup-ture in group 1 was significantly higher than that in the other groups. On the other hand, the favorable outcome rate (excellent and good) was as follows: group 1: 40%; group 2: 73%; group 3: 22%. This rate was sig-nificantly higher in patients who received normotensive hypervolemic therapy, than in other groups.

This study suggests that, to avoid rerupture and un-favorable outcome, normotensive hypervolemic therapy is the optimal management approach in patients with DIND after SAH who have not undergone obliteration of the aneurysmal neck.


Copyright © 1995, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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