雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Bone and calcium metabolism associated with malignancy. The interaction of bone pain and cancer progression. Okui Tatsuo pp.1473-1478
Published Date 2018/10/28
DOI https://doi.org/10.20837/42018111473
  • Abstract
  • Look Inside
  • Reference

 Cancer cell preferentially colonize or metastasize to bone. Although the mechanism of bone metastasis still remains poorly understood, cancer cell that metastasize to bone negatively perturb the remodeling process through a series of interactions with osteoclasts, and osteoblasts. These "vicious cycle" promote cancer progression in bone.  Sensory neuron innervated in bone is regarded as component of bone microenvironment. Recent study indicated that peripheral neuron system(PNS)promote cancer progression in bone. These insights indicated sensory neuron suppression results in newly cancer treatment of bone metastasis. Here we reviewed the recent findings of interaction between cancer progression and sensory neuron activation in bone.



基本情報

電子版ISSN 印刷版ISSN 0917-5857 医薬ジャーナル社

関連文献

もっと見る

文献を共有