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Bone Cell Biology Assessed by Microscopic Approach. A mathematical approach to understand bone remodeling. Kameo Yoshitaka 1 , Adachi Taiji 2 1Department of Biomechanics, Institute for Frontier Medical Sciences, Kyoto University, Japan. 2Department of Biomechanics, Institute for Frontier Medical Sciences, Kyoto University, Japan. pp.1475-1481
Published Date 2015/9/28
DOI https://doi.org/10.20837/4201510053
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 It is well known that bone tissue can change its outer shape and internal structure by remodeling according to a changing mechanical environment. However, the mechanism of bone functional adaptation induced by the collaborative metabolic activities of bone cells in response to mechanical stimuli remains elusive. In this article, we focus on the hierarchy of bone structure and function from the microscopic cellular level to the macroscopic tissue level. We provide an overview of a mathematical approach to understand the adaptive changes in trabecular morphology under the application of mechanical stress.



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電子版ISSN 印刷版ISSN 0917-5857 医薬ジャーナル社

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