Japanese
English
- 有料閲覧
- Abstract 文献概要
- 1ページ目 Look Inside
- 参考文献 Reference
肺気腫に対する外科療法としては今日までに肺容量減量手術(LVRS),肺移植などが有効性を実証されてきたが,わが国ではNational Emphysema Treatment Trial(NETT)studyの結果以降にLVRS症例は減少し,またドナーの問題により肺移植の適応となる症例は少ないため,気管支鏡的肺容量減量術(BLVR)が今後の有効な治療法として期待される状況である.一方で,BLVRよりもLVRSが有効な症例も存在することが予想される.また,そのうえで術後合併症を安全に制御することは重要である.当科では1999~2024年の胸腔鏡下手術約10,000件中,LVRSを22例で施行した.このうち1例を提示し,手術適応や治療経過および手術手技を再考する.
Lung volume reduction surgery (LVRS) and lung transplantation have proven to be effective surgical treatments for emphysema. However, since the results of the National Emphysema Treatment Trial (NETT) study, there has been a sharp decline in the number of LVRS cases in Japan, and few patients are eligible for lung transplantation due to donor problems, so bronchoscopic lung volume reduction (BLVR) is expected to be an effective treatment in the future. In our department, LVRS was performed in 22 cases out of approximately 10,000 thoracoscopic procedures from 1999 to 2024. The overall postoperative forced expiratory volume in on second (FEV1.0) improvement rate was 45%, especially 61% for bilateral surgery. If postoperative complications can be safely controlled, LVRS can be expected to have better outcomes than BLVR for bilateral upper lobe dominant forms of emphysema.

© Nankodo Co., Ltd., 2025