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肺区域切除を施行するうえで,術前3D画像(特に肺動脈の灌流域による区域間認識と腫瘍からのマージン距離確認)を用いて詳細な切離区域の設定を行い,インドシアニングリーン(ICG)静注法により術前に設定した区域間を同定し,術前のシミュレーションどおりの手術を行うことで,適切なマージン確保をめざしている.この二つの方法は,いずれも肺動脈の灌流に基づいており,有用な手段であると考えている.本稿では,上記方法で施行した肺区域切除例を後方視的に検討し,本法によるマージン確保の有用性,問題点について検討する.
Purpose:When performing segmentectomy, we aim to keep adequate distance from the tumor using three-dimensional (3D) images of the pulmonary artery perfusion area and the indocyanine green (ICG) injection method. The effectiveness and improvement of this method were examined.
Patients and method:We retrospectively investigated 50 consecutive patients who underwent segmentectomy with this method. In simulation, we measured the predicted margin distance (PMD) on a 3D image. Then, we measured the actual margin distance (AMD) on resected specimens fixed in formalin. We compared these two distances and evaluated factors influencing shorter AMD.
Results:The median AMD was 1.7 cm, and there was no positive margin case. The median ratio of AMD/PMD was 0.73. In multivariate analysis, shorter PMD and no resection of subsegment bronchi next to the tumor were significant factors associated with shorter AMD (p<0.001, p=0.014).
Conclusions:Our method was effective for segmentectomy. For adequate AMD, a longer PMD in simulation and subsegmental bronchi resection next to the tumor should be considered.
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