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Thoracic Endovascular Aortic Repair for Mycotic Thoracic Aortic Aneurysm After BCG Intravesical Therapy Hayato Obi 1 , Kanetsugu Nagao 1 , Masaya Aoki 1 , Saori Nagura 1 , Shigeyuki Yamashita 1 , Toshio Doi 1 , Akio Yamashita 1 , Kazuaki Fukahara 1 , Naoki Yoshimura 1 , Keiju Kotoh 2 1Department of Thoracic and Cardiovascular Surgery, University of Toyama Keyword: BCG intravesical therapy , mycotic aortic aneurysm , thoracic endovascular aortic repair pp.1083-1089
Published Date 2023/12/1
DOI https://doi.org/10.15106/j_kyobu76_1083
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Bacille Calmette-Guérin (BCG) intravesical therapy is an effective and safe treatment for bladder cancer;however, mycotic aneurysms have been reported as a rare complication.

Case 1:A 64-year-old man with a history of BCG intravesical therapy underwent emergent thoracic endovascular aortic repair (TEVAR) for a ruptured thoracic aortic aneurysm (TAA). He was diagnosed with BCG infection by hemosputum specimen culture five months later;then, antituberculous therapy was initiated. However, his follow-up computed tomography scan revealed stent-graft infection and new aneurysm formation. Therefore, we performed a repeated TEVAR with abdominal 4-vessel debranching. There was no recurrence of infection for six years while continuing postoperative antituberculous therapy.

Case 2:A 72-year-old man who had undergone BCG intravesical therapy underwent TEVAR for a rapidly enlarging mycotic TAA. He received anti-tuberculous therapy for one year with no recurrent infection for one year. TEVAR may be an effective alternative to the open surgical procedure;however, multidisciplinary treatment including anti-tuberculous therapy and careful long-term follow up are required.


© Nankodo Co., Ltd., 2023

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電子版ISSN 2432-9436 印刷版ISSN 0021-5252 南江堂

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