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The Influence of Stimulating Factors During Delivery on Interleukin-1 in Human Colostrum Yumiko Tateoka 1 , Kiyomi Kitamura 1 1University of Shizuoka, School of Nursing Keyword: 初乳 , インターロイキン1 , 分娩刺激因子 , human colostrum , Interleukin-1 , Stimulant factors during delivery pp.31-37
Published Date 2000/6/30
DOI https://doi.org/10.11477/mf.7009200144
  • Abstract
  • Reference

Abstract

 Interleukin-1α and interleukin-1β concentrations in human colostrum from 85 mothers were investigated by enzyme immunoassay. The reletions between the interleukin-1 concentrations and maternal obstetric factors were examined.

 The mean values and standard deviation of the interleukin-1α and interleukin-1β concentrations were 19.6±12.7 pg/ml and 53.7±106.6 pg/ml, respectively. Wide variations in interleukin-1α and interleukin-1β concentrations among individuals were found in human colostrum at 3 days postpartum. Among the obstetric factors, duration of labor, amount of postpartum bleeding, intensity of uterine contractions, placental weight, and infection were significantly correlated with the concentration of interleukin-1α , suggesting that interleukin-1α-stimulating factors during delivery promoted the secretion of interleukin-1α in the mammary glands.

 These finding showed that the colostrum of stimulant mothers during delivery contains more interleukin-1α . These scientific facts are reflected in a breastfeeding plan and are evidence based on nursing practice.


Copyright © 2000, Japan Society of Nursing and Health Care All rights reserved.

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電子版ISSN 印刷版ISSN 1345-2606 日本看護医療学会

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