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Japanese Occupational Therapy Research Volume 20, Issue 1 （February 2001）

作業療法 20巻1号（2001年2月発行）

Japanese English

◆研究と報告

作業活動の精神機能，身体機能への影響について—STAI，NK活性を用いた定量的評価の試み，第一報 The effect of the therapeutic activities on mental and physical function: A preliminary study using STAI and NK activity for quantitative analysis,the first report 高原世津子 ¹ , 高橋清之 ² , 山根寛 ³ , 小西紀一 ³ , 中村孝志 ⁴ Setsuko Takahara ¹ , Kiyoyuki Takahashi ² , Hiroshi Yamane ³ , Norikazu Konishi ³ , Takashi Nakamura ⁴ ¹京都大学医学部附属病院理学療法部 ²老人保健施設ライフポート茨木 ³京都大学医療技術短期大学部作業療法学科 ⁴京都大学医学部附属病院整形外科 ¹Department of Physical Therapy, Kyoto University Hospital ²Geriatric Health Services Facility, Life Port Ibaraki ³Division of Occupational Therapy, College of Medical Technology, Kyoto University ⁴Department of Orthopaedic Surgery, Kyoto University キーワード：作業活動 , (NK活性) , (STAI) , Occupational activities , Natural killer cell activity , State-Trait Anxiety Inventory Keyword: 作業活動 , (NK活性) , (STAI) , Occupational activities , Natural killer cell activity , State-Trait Anxiety Inventory pp.52-59

発行日 2001年2月15日 Published Date 2001/2/15

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要旨：作業療法における手工芸的な作業活動の精神機能，身体機能への影響を，状態・特性不安検査(STAI)とナチュラルキラー(NK)細胞の活性度を指標に検討した．被験者は当院において作業療法を行っている，上肢に何らかの機能障害をもつ進行性の神経疾患などの患者である．STAI検査により作業活動後，状態不安が減少することが示された．NK活性は今回の研究では作業活動の前後において有為な変化はみられなかったが，実験方法をさらに厳密に調整することによって，NK活性を用いて作業活動の効果を客観的に表現する可能性が示唆された．

　One characteristic of occupational therapy involves the use of therapeutic activities. These purposeful activities are believed to contribute to the promotion of healthier minds and bodys.

　The purpose of this study is to measure quantitatively the effect of the activities in occupational therapy. For this purpose, we used State-Trait Anxiety Inventory (STAI) and natural killer (NK) cell activity as indices. At the same time, we measured blood pressure and pulse rate. The subjects were fifteen patients who received occupational therapy in our hospital. They had functional disorder in their upper extreamities and most of them had progressive neurological illness. We checked STAI, NK activity, blood pressure and pulse rate before and after the activity. In the STAI, the state anxiety of the subjects reduced significantly (p＜0.01) following the activities of occupational therapy. On the other hand, there was no change in NK activity. Among 15 subjects, nine of them came on foot, and six of them came on a wheelchair. The ambulatory group showed a high NK activity level even before the occupational therapy and resulted in little change after the therapy. On the other hand, NK activity level of the wheelchair group was 20% lower than that of the ambulatory group and resulted in 30% gain after the therapy. Edwards reported that an exercise raised the NK activity level; thus the above mentioned condition could be related with the difference of locomotion. It was suggested that a possibility that the effects of occupational therapy can be proved effective quantitatively by use of NK activity under more strict experimental conditions.