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要旨:再生医療の治験を受けて5ヵ月が経過しても重度上肢麻痺を呈した慢性期脳卒中患者に,装具療法と電気刺激療法を併用した課題指向型アプローチを22週間(1日1時間,週3回)実施した.結果,対象者のFugl-Meyer Assessment, Motor Activity LogのAmount of useが,過去の研究で示された慢性期のMinimal Clinically Important Differenceを超えて変化した.先行研究では,再生医療による慢性期脳卒中患者における上肢機能への大きな効果は,実施後3ヵ月程度と報告されている.よって,本症例においては,多角的な練習が上肢機能を改善させた可能性がある.
We treated severe arm paresis in a chronic stroke patient who underwent regenerative therapy five months ago, using the task-oriented training combined with orthosis and electrical stimulation therapy for 22 weeks (1 hour a day, 3 times a week). Consequently, the patient's Fugl-Meyer Assessment scores and the Amount of Use scores in the Motor Activity Log improved more than those in previous studies. Previous studies showed that the efficacy of regenerative medicine for paretic arms in a chronic stroke patient lasts for about 3 months post intervention. Therefore, this case study shows that multiple interventions might improve arm function.
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