CONFERENCE ON THE CHEMISTRY OF MUSCULAR CONTRACTION 1957
Some Physical and Enzymatic Phenomena in Solutions of Myosin B
PETER H. VON HIPPEL
1
,
MARTIN F. GELLERT
1
,
MANUEL F. MORALES
1
1Division of Physical Biochemistry, Naval Medical Research Institute, National Naval Medical Center
pp.53-65
発行日 1958年4月15日
Published Date 1958/4/15
DOI https://doi.org/10.11477/mf.2425905992
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Although "myosin B," the isolable contractile substance of muscle, has been the object of worldwide study, its nature remains controversial.By most workers it is thought to be a compound of myosin(or "myosin A")and actin-formable by combination of actin and myosin, and dissociable ([KCl]≧.5) upon addition of ATP.But a few workers have not agreed with all features of this hypothesis.For example, Tsao's observations on the rotaional relaxation time of actin in the presence of myosin were considered by him to be incompatible with assuming that actin forms a compound with myosin(1).
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