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片頭痛は生活への支障が大きい疾患であり,特に20〜40代の女性での有病率が高い。片頭痛の病態には女性ホルモンの変動が関与していると考えられており,女性のライフステージによってさまざまな影響を受ける。重症度の高い月経時片頭痛の治療,子宮内膜症を合併した場合の治療法,妊娠・授乳中の薬剤選択など,常に患者の優先事項を確認し,患者とともに治療を選択・支援することが重要である。
Abstract
Migraine is a neurological disorder characterized by a high degree of disruption to life. The prevalence of migraines is high among women in their 20s to 40s. The hormonal milieu has a substantial effect on migraines in women. An understanding of these hormonal influences at various stages of life (menstrual cycle, pregnancy, puerperium, menopause, and use of hormone therapy) is essential for the management and prevention of migraines. It is important to identify patients' priorities and consider them to select and support treatment options, such as the treatment of severe menstrual migraine, treatment options when complicated by endometriosis, and the choice of medication during pregnancy and lactation.

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