Crohn's disease and ulcerative colitis Masahiro Suzuki 1 , Takashi Nagaishi 1 , Mamoru Watanabe 1 1Department of Gastroenterology, Graduate School of Medical Science, Tokyo Medical and Dental University Keyword: 炎症性腸疾患 , 潰瘍性大腸炎 , Crohn病 pp.1258-1264
Published Date 2011/10/30
DOI https://doi.org/10.11477/mf.1542102811
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Recent progress in immunology and molecular biology have led to the evidence that the etiologies of inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis may be associated with not only the genetic background of the patients but also with environmental factors by which are induced superfluous immune responses to antigens derived from commensal micro biota and/or foods as well as collapse of the mucosal barrier function. Explained in this review are basic knowledge and understanding regarding mucosal immunology in the gut associated with the pathophysiology of IBD.

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