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IgG4-related respiratory disease Shoko Matsui 1 1University of Toyama, Health Administration Center Keyword: 高IgG血症 , 高IgG4血症 , 高IgE血症 pp.783-788
Published Date 2011/8/15
DOI https://doi.org/10.11477/mf.1542102699
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Immunoglobulin G4 (IgG4)-related disease is a new concept concerning multi-organ disease, which involves respiratory systems. Clinically, the respiratory disease occurs predominantly in elderly men. They are usually asymptomatic, but some cases present bronchial asthma-like symptoms. Chest CT shows various findings, such as thickening of broncho-vascular bundle with or without infiltration, interlobular thickening, tumor-like lesions, pleural abnormalities, and lymphadenopathy. In laboratory data, the patients present high levels of serum IgG, IgG4 and IgE. Pathologically, abundant plasma cell infiltration has been observed in various inflamed areas. The diagnostic consensus of IgG4-related respiratory disease has not been established yet. A large scale prospective study is required to clarify the feature and treatment of IgG4-related respiratory disease.


Copyright © 2011, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1367 印刷版ISSN 0485-1420 医学書院

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