脳神経外科領域における新しい医療材料と感染症

Development of Medical Materials and Infection

Point

・他家血液・組織由来の医療材料を使用する際には，感染のリスクを考慮する必要がある．

・創部感染を予防するために抗菌性を備えた医療材料が開発され，その有効性を検証するために多くの研究が行われている．

　Surgery has the possibility to cause infections. Surgical site infection（SSI）is a common complication of various surgical procedures. On the other hand, allogeneic tissue-derived material-induced infections, such as transfusion-related hepatitis and Creutzfeldt-Jakob disease, are rare but occur. The risk of surgery-related infections needs to be reduced because such infections not only affect morbidity and mortality but also lead to increased medical costs and longer hospitalization. Recently, various allogeneic and synthetic medical materials have been developed, and many types of materials have been used in daily neurosurgical procedures. Some synthetic materials have been advertised to have an SSI-preventive effect. Technology has also been developed to minimize the infectivity of allogeneic materials. In this paper, we introduce some information focused on the infectivity of fibrin glue and DuraGen^® and the SSI-preventive effect of Surgicel^® and antimicrobial sutures.