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Postoperative Neurological Deficit due to Transient Hypoperfusion in the Pretreated Contralateral Hemisphere after Bypass Surgery in an Adult Patient with Moyamoya Disease:A Case Report Saya OZAKI 1 , Shiro OHUE 1 , Shinji IWATA 1 , Shinya FUKUMOTO 1 , Haruhisa ICHIKAWA 1 , Shinji ONOUE 1 , Akihiro INOUE 1 , Yawara NAKAMURA 1 , Kanehisa KOHNO 1 1Department of Neurosurgery, Stroke Center, Ehime Prefectural Central Hospital Keyword: moyamoya disease , cerebral blood flow , hyperperfusion , hypoperfusion , postoperative neurological deficit pp.391-399
Published Date 2018/5/10
DOI https://doi.org/10.11477/mf.1436203740
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 Postoperative neurological deficits frequently occur in adult moyamoya disease. In this case report, we describe the time course and disease state of a patient with adult moyamoya disease, who experienced a postoperative neurological deficit due to transient hypoperfusion in the pretreated contralateral hemisphere.

 A 68-year-old female presented with a sudden onset of left hemianopia due to ischemic moyamoya disease. She had severely low cerebral blood flow(CBF)in the right hemisphere and deterioration of cerebrovascular reactivity in the left hemisphere. First, right combined bypass surgery was performed;subsequently, left combined bypass surgery was performed. Two days after left hemisphere surgery, left hemiparesis gradually appeared. Hypoperfusion of the right hemisphere and hyperperfusion of the left hemisphere were revealed by SPECT and CT perfusion imaging. Blood pressure was controlled to normal levels, and an antiepileptic drug, antiplatelet drug, and edaravone were administered. The patient gradually recovered 2 weeks later, and was able to resume her normal daily life. During the clinical course, laterality of CBF was improved following improvement of clinical symptoms.

 Abnormal postoperative disproportion of the CBF may occur after revascularization surgery for adult moyamoya disease. Prompt assessment of CBF and proper treatment are needed.


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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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