頭蓋骨に発生したIdiopathic Massive Osteolysisの1例

Idiopathic Massive Osteolysis of Skull Bone: A Case Report

I．はじめに

　Idiopathic massive osteolysisは進行性の骨融解が起こる原因不明の稀な疾患であるが，頭蓋骨に発生したものはさらに稀である．最近上記と思われる1例を経験したので文献的考察を加えて報告する．

A rare case of idiopathic massive osteolysis of the skull is reported. A 49 year-old male was admitted with a diagnosis of a skull tumor. The skull film taken for evaluation of the headache, showed a large lytic lesion with irregular margin in the left parietal area. CT showed that some of the hone had been destroyed, but the underlying brain was normal. Technetium 99m-MDP bone scan showed high activity around the mar-gin of the lytic lesion. During surgery for this bone le-sion no neoplastic or inflammatory changes were re-vealed. However, destruction of the bone without new bone formation could be seen.