動眼神経の修復と再生に関する実験的研究

Oculomotor Nerve Anastomosis: An experimental study in the dog

I．はじめに

　動眼神経は頭蓋内手術操作で損傷を受けることがある．特に最近，手術手技，器具の進歩に伴って手術適応の範囲が拡大し，その危険性はかえって高まっているように思える．

　このような損傷の際の修復再建の可能性に関して検討を試みた基礎的実験は，現在までのところ見出せず，臨床例では，岩淵ら（1982）^14）がトルコ鞍左側に進展著しい下垂体腺腫摘出の際やむなく断裂された動眼神経に対して吻合を試みた1例の報告が検索されるのみである．

For the purpose of inverstigating the ability of posttraumatic oculomotor nerve to restore its function, animal experiments were carried out using 22 mongrel adult dogs weighting 6.5kg on the average. Anesthesia was induced with 30mg/kg of intervenous Nembutal, and craniectomy performed. An injury was delivered to the oculomotor nerve at about 2mm centrally from the rim of the tentorium which was reached by retracting the temporal lobe under the oprating microscope, then the wound was closed.