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2016 WHO Classification of Tumors of CNS: A Paradigm Shift from Histologic to Molecular Classification Takanori Hirose 1,2 1Pathology for Regional Communication, Kobe University School of Medicine 2Department of Diagnostic Pathology, Hyogo Cancer Center Keyword: 脳腫瘍 , WHO中枢神経系腫瘍分類 , 分子分類 , びまん性膠腫 , 胎児性腫瘍 , brain tumor , WHO classification of CNS tumors , molecular classification , diffuse gliomas , embryonal tumors pp.543-550
Published Date 2018/5/1
DOI https://doi.org/10.11477/mf.1416201036
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Abstract

With the recent development in molecular genetics, the WHO classification of CNS tumors was revised in 2016. The new WHO classification made a paradigm shift from traditional histologic classification to molecular classification. In particular, integrated diagnoses that combined morphologic and molecular information were introduced for diffuse gliomas and embryonal tumors. The new classification is expected to result in more accurate diagnosis, appropriate therapeutic strategy, precise prediction of prognosis, etc. Practical efforts have already been started at the clinical sites to adapt to the new classification.


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電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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