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Cognitive Impairment in Multiple Sclerosis Masaaki Niino 1 , Yusei Miyazaki 1,2 1Departments of Clinical Research, Hokkaido Medical Center 2Departments of and Neurology, Hokkaido Medical Center Keyword: 多発性硬化症 , 認知機能 , 神経心理学的簡易反復検査法 , 治療 , multiple sclerosis , cognition , brief repeatable battery of neuropsychological tests , therapy pp.375-381
Published Date 2016/4/1
DOI https://doi.org/10.11477/mf.1416200408
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Abstract

While cognitive impairment is a major symptom of multiple sclerosis (MS), it is commonly overlooked. This may be explained by the fact that it is difficult to evaluate cognitive function in patients with MS using screening batteries for the detection of dementia such as the mini-mental state examination. Further more, cognitive impairment in MS typically involves domain-specific deficits such as imparement of sustained attention and information processing speed rather than global cognitive decline. Cognitive impairment may influence the daily living and social lines of affected patients. This review discusses the characteristics of cognitive impairment, appropreate tests to evaluate its symptoms, and the current status of clinical trials for the treatment of MS.


Copyright © 2016, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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