Dominant Thalamus and Aphasia Akiko Nakano 1 , Tatsuo Shimomura 2,3 1Department of Therapy for Speech, Language and Hearing, Akita Prefectural Center for Rehabilitation and Psychiatric Medicine 2Akita Prefectural Center for Rehabilitation and Psychiatric Medicine 3Department of Treatment for Dementia, Akita Prefectural Center for Rehabilitation and Psychiatric Medicine Keyword: 視床失語 , 脳幹網様体賦活系 , 言語性記憶障害 , 皮質の賦活障害 , 超皮質性失語 , thalamic aphasia , cortical de-facilitation , verbal memory deficit , brainstem reticular activating system , transcortical aphasias pp.1495-1498
Published Date 2015/12/1
DOI https://doi.org/10.11477/mf.1416200327
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Many studies have shown that lesions of the dominant thalamus precipitate language disorders in a similar manner to transcortical aphasias, in a phenomenon known as "thalamic aphasia." In some cases, however, aphasia may not occur or may appear transiently following thalamic lesions. Furthermore, dominant thalamic lesions can produce changes in character, as observed in patients with amnesic disorder. Previous work has explored the utility of thalamic aphasia as a discriminative feature for classification of aphasia. Although the thalamus may be involved in the function of the brainstem reticular activating system and play a role in attentional network and in memory of Papez circuit or Yakovlev circuit, the mechanism by which thalamic lesion leads to the emergence of aphasic disorders is unclear. In this review, we we survey historical and recent literature on thalamic aphasia in an attempt to understand the neural processes affected by thalamic lesions.

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