点状角化症の1異型

ATYPICAL FORM OF KERATOSIS PUNCTATA

　手掌に角化性丘疹や小陥凹をきたす疾患にはいくつかあるが，ここに述べる症例は両手掌のしわ，すなわち皮膚線に一致して発生したものであり，このような臨床像はかなり特徴的であるにもかかわらず報告は少なく，その名称についても報告者により異なつている．

　自験例では組織学的に汗孔に一致して角栓形成を認めたが，このような所見はこれまでに報告された類似症例では見いだされていない．

A 28-year-old man had found keratotic papules and small depression on the folds of the palms, which were 8 in number at his first visit. The small depression was a secondary change after the removal of the small keratotic plugs from the papules with needle.

Histologic specimen from the depression showed the depressed epidermis and hyperkeratosis and acanthosis. Specimen from the papules showed the keratotic plugging, hyperkeratosis and funnel-shaped depression of the epidermis, through the center of which the intraepidermal sweat duct was running.

This ease resembled "a new type of symmetrical punctate keratosis" by Matsumoto, and cases re-ported by Arnold or Fischer. The histologic finding of this case which showed the papules accompanied with the sweat pore corresponded to the Matsumoto's case.

The nature of this disease is unknown. Although Arnold of Fischer regarded the disease as an atypical type of Kyrle's disease, there are many points which differ from Kyrle's disease. The author regarded the ease as a type of Keratosis punctata according to Matsumoto.