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APOCRINE CYSTADENOMA Tetsuo YAMAMOTO 1 , Takuo TSUJI 1 , Tetsuro SUGAI 1 1Department of Dermatology, Osaka City University Medical School pp.145-149
Published Date 1970/2/1
DOI https://doi.org/10.11477/mf.1412200615
  • Abstract
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A case of apocrine cystadenoma in a 48-year-old Japanese man who presented witha slightly reddish, semispherically raised, sessile cystic nodule of 8 mm. in diameter on the left outer canthus. is reported Microscopic studies of sections of the tumor revealed a large cystic space encapsulated with fibrous tissues in the corium. The cyst was lined by one to several layers of secretory epithelium. There were another lumen filled with nests of secretory cells and a dilated secretory duct in the vicinity of the large cyst. The glandular lumen was lined with outer layer of cuboidal immature myoepithelial cells and inner layers of columnar cylind-ric al cells. Enzymatic studies disclosed that the secretory cells were most likely of apocrine origin. The dilated duct was composed of two layers of cuboidal cells, and there was diastase-resistant, PAS-positive secretory debris in the lumen.

Apocrine cystadenoma would not be a retention cyst, but a benign nevoid tumor of apocrine duct origin, because the cystic space was encapsulated with fibrous stroma, and the tumor cells were proliferative and related to the apocrine gland. In view of the fact that the tumor occurred on the canthus, it would be reasonable to consider that it originated from the Moll's gland. To our best knowledge, this is the first confirmed case of apocrine cystadenoma in the Japanese dermatological field.


Copyright © 1970, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1324 印刷版ISSN 0021-4973 医学書院

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